Anti-DNMT3A antibody

Anti-DNMT3A antibody

Cat. No.     JC120559        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-DNMT3A rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human DNMT3A
Reactivity                 Human, Mouse, Rat
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-DNMT3A antibody
Target information
Symbol                 DNMT3A
Full name                 DNA (cytosine-5-)-methyltransferase 3 alpha
Synonyms    DNMT3A2, M.HsaIIIA
Swissprot    Q9Y6K1

Target Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Anti-DNMT3A antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Nucleus
Positive control: Human stomach cancer
Recommended dilution: 100-300