Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
适应物种:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
免疫原:
详见说明书
亚型:
IGg
形态:
粉末、液体、冻干粉
应用范围:
ICC=1:50-200 IF=1:50-200
浓度:
1mg/ml
保存条件:
-20 °C
规格:
100ul
FITC标记的周期素Y/X抗体
英文名称
Anti-Cyclin Y/FITC
中文名称
FITC标记的周期素Y/X抗体
别 名
C10orf9; CBCP1; CCNX; CCNY; CFP1; Chromosome 10 open reading frame 9; Cyclin box carrying protein 1; Cyclin box protein 1; Cyclin fold protein 1; Cyclin X; Cyclin Y; CCNY_HUMAN.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
肿瘤 细胞生物 信号转导 细胞周期蛋白 表观遗传学
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
产品应用
ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
39kDa
细胞定位
细胞膜
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human Cyclin Y/Cyclin X
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: Cyclin Y is a 341 amino acid protein belonging to the cyclin family. Cyclin Y exists as three alternatively spliced isoforms and contains a cyclin N-terminal domain. Cyclin Y may control cell division cycles and regulate cyclin-dependent kinases. Cell proliferation is controlled at specific stages of the cell cycle by distinct protein kinase complexes. These complexes consist of a catalytic subunit associating with a specific regulatory subunit to form the active kinase. The cyclins, which include cyclin A, B, C, D, E, F, G, H, I, K, L, T, Y and their related proteins, including Dbf4, comprise the regulatory subunits of these kinase complexes. The controlled activation of the kinase complexes at various intervals of the cell cycle is regulated by the availability of the cyclins to the catalytic subunit. Unlike the catalytic subunit, which is expressed continually, the expression and stability of the regulatory subunit fluctuates depending on the stage of the cell cycle, thereby regulating kinase activity.
Function: Cyclin Y is a cyclin which plays a role in the control of cell division cycles and regulation of cyclin dependent kinases (e.g., CDC2; MIM 116940). Single nucleotide polymorphism in Cyclin Y gene is associated with Crohn's disease and ulcerative colitis.