- 询价
- elatins
- JLC260776
- 上海
- 2025年07月08日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-TRAF3 antibody
- 宿主：
Rabbit
- 浓度：
0.2 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Cat. No. JLC260776
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-TRAF3 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human TRAF3
Reactivity Human, Mouse
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol TRAF3
Full name TNF receptor-associated factor 3
Synonyms CAP1, LAP1, CAP-1, CRAF1, IIAE5, CD40bp
Swissprot Q13114
Target Background
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml260776(TRAF3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:64 kDa
Positive control:Mouse kidney tissue
Recommended dilution: 200-1000
Gel: 8+10+12%SDS-PAGE
Lysate: 60 μg
Lane: Mouse kidney tissue
Primary antibody: ml260776(TRAF3 Antibody) at dilution 1/300
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 40 seconds
ELISA
Recommended dilution: 1000-5000
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