Product overview
Description Anti-EPS15 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human EPS15
Reactivity Human, Mouse
Content 1.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol EPS15
Full name epidermal growth factor receptor pathway substrate 15
Synonyms AF1P; AF-1P; MLLT5
Swissprot P42566
Target Background
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.