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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体名:
Anti-IFNB1 antibody
- 适应物种:
人/动物/植物
- 浓度:
1.1 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JLC163031
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-IFNB1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human IFNB1
Reactivity Human
Content 1.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol IFNB1
Full name interferon, beta 1, fibroblast
Synonyms IFB; IFF; IFNB; IFN-beta
Swissprot P01574
Target Background
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
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