Product overview
Description Anti-DEGS1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human DEGS1
Reactivity Human, Mouse, Rat
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol DEGS1
Full name delta(4)-desaturase, sphingolipid 1
Synonyms MLD; DEGS; DES1; Des-1; FADS7; MIG15; DEGS-1
Swissprot O15121
Target Background
This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.