Product overview
Description Anti-KLF5 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human KLF5
Reactivity Human, Mouse
Content 0.8 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol KLF5
Full name Kruppel like factor 5
Synonyms CKLF; IKLF; BTEB2
Swissprot Q13887
Target Background
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants.