Anti-SNX6 antibody

Anti-SNX6 antibody

Cat. No.     JK263603       
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SNX6 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human SNX6
Reactivity                 Human, Mouse
Content                     1.9 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification


Target information
Symbol                 SNX6
Full name                 sorting nexin 6
Synonyms    TFAF2; MSTP010
Swissprot    Q9UNH7

Target Background
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.