Product overview Description Anti-KCNH3 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Synthetic peptide of human KCNH3 Reactivity Human, Mouse, Rat Content 0.1 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol KCNH3 Full name potassium voltage-gated channel, subfamily H (eag-related), member 3 Synonyms BEC1, ELK2, Kv12.2 Swissprot Q9ULD8
Target Background Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit. Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly. The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Detected only in brain, in particular in the telencephalon. Detected in the cerebral cortex, occipital pole, frontal and temporal lobe, putamen, amygdala, hippocampus and caudate nucleus.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml260471(KCNH3 Antibody) at dilution 1/12, on the right is treated with synthetic peptide. (Original magnification: ×200)