Product overview Description Anti-GRM5 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human GRM5
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol GRM5
Full name glutamate receptor, metabotropic 5
Synonyms mGlu5; GPRC1E; MGLUR5; PPP1R86
Swissprot P41594
Target Background This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.