Product overview Description Anti-PF4 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human PF4
Reactivity Human
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol PF4
Full name platelet factor 4
Synonyms PF-4; CXCL4; SCYB4
Swissprot P02776
Target Background This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.