Anti-HTR2A antibody

Anti-HTR2A antibody

Cat. No.     JLC162769
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-HTR2A rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human HTR2A
Reactivity                 Human
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification



Target information
Symbol                 HTR2A
Full name                 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
Synonyms    HTR2; 5-HT2A
Swissprot    P28223

Target Background
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.