Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
适应物种:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
免疫原:
详见说明书
亚型:
IGg
形态:
粉末、液体、冻干粉
应用范围:
ICC=1:50-200 IF=1:50-200
浓度:
1mg/ml
保存条件:
-20 °C
规格:
100ul
FITC标记的RNA结合蛋白15抗体
英文名称
Anti-RBM15/FITC
中文名称
FITC标记的RNA结合蛋白15抗体
别 名
One twenty two protein; OTT; OTT1; SPEN; RNA binding motif protein 15; RBM15_HUMAN.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
肿瘤 染色质和核信号 干细胞 淋巴细胞 b-淋巴细胞
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
产品应用
ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
107kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human RBM15
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]
Function: Rbm15 plays an important role in hematopoietic development, with pleiotropic effects in the stem cell, lymphoid, and myeloid compartments.
Subunit: Interacts with Epstein-Barr virus BSFL2/BMLF1.
Subcellular Location: Nuclear.
DISEASE: Note=A chromosomal aberration involving RBM15 may be a cause of acute megakaryoblastic leukemia. Translocation t(1;22)(p13;q13) with MKL1. Although both reciprocal fusion transcripts are detected in acute megakaryoblastic leukemia (AMKL, FAB-M7), the RBM15-MKL1 chimeric protein has all the putative functional domains encoded by each gene and is the candidate oncogene.
Similarity: Belongs to the RRM Spen family. Contains 3 RRM (RNA recognition motif) domains. Contains 1 SPOC domain.
Database links:
Entrez Gene: 64783 Human
Omim: 606077 Human
SwissProt: Q96T37 Human
Unigene: 435947 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.