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- 详细信息
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-BBC3 antibody
- 宿主:
Rabbit
- 浓度:
0.9 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Anti-BBC3 antibody
Cat. No. JLC260118
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-BBC3 rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Synthetic peptide of human BBC3
Reactivity Human
Content 0.9 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol BBC3
Full name BCL2 binding component 3
Synonyms JFY1; PUMA; JFY-1
Swissprot Q9BXH1
Target Background
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

Applications
Western blotting
Predicted band size:21 kDa
Positive control:A549 cells
Recommended dilution: 200-1000
Gel: 10%SDS-PAGE
Lysate: 40 μg
Lane: A549 cells
Primary antibody: ml260118(BBC3 Antibody) at dilution 1/600
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 5 minutes
ELISA
Recommended dilution:1000-2000
Cat. No. JLC260118
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-BBC3 rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Synthetic peptide of human BBC3
Reactivity Human
Content 0.9 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol BBC3
Full name BCL2 binding component 3
Synonyms JFY1; PUMA; JFY-1
Swissprot Q9BXH1
Target Background
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

Applications
Western blotting
Predicted band size:21 kDa
Positive control:A549 cells
Recommended dilution: 200-1000
Gel: 10%SDS-PAGE
Lysate: 40 μg
Lane: A549 cells
Primary antibody: ml260118(BBC3 Antibody) at dilution 1/600
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 5 minutes
ELISA
Recommended dilution:1000-2000
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Anti-BBC3 antibody
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