Product overview
Description Anti-CHRNA5 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CHRNA5
Reactivity Human, Rat
Content 1.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CHRNA5
Full name cholinergic receptor, nicotinic alpha 5
Synonyms LNCR2
Swissprot P30532
Target Background
The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010]