Anti-STS antibody

Anti-STS antibody

Cat. No.     JLC162305
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-STS rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human STS
Reactivity                 Human
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification



Target information
Symbol                 STS
Full name                 steroid sulfatase (microsomal), isozyme S
Synonyms    ES; ASC; XLI; ARSC; SSDD; ARSC1
Swissprot    P08842

Target Background
This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726).