Anti-RAD54B antibody

Anti-RAD54B antibody

Cat. No.     JLC162105
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-RAD54B rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human RAD54B
Reactivity                 Human
Content                     0.8 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 RAD54B
Full name                 RAD54 homolog B (S. cerevisiae)
Synonyms    RDH54
Swissprot    Q9Y620

Target Background
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.