- 询价
- gelatins
- JLC225592
- 上海
- 2025年07月13日
- Rabbit
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- 详细信息
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-JPT1 antibody
- 宿主：
Rabbit
- 浓度：
0.6 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-JPT1 antibody
Cat. No. JLC225592
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-JPT1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human JPT1
Reactivity Human, Mouse, Rat
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol JPT1
Full name Jupiter microtubule associated homolog 1
Synonyms HN1; ARM2; HN1A
Swissprot Q9UK76
Target Background
Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
Applications
Immunohistochemistry
Predicted cell location: Nucleus and Cell membrane
Positive control: Human tonsil
Recommended dilution: 40-200 Predicted cell location: Nucleus and Cell membrane
Positive control: Human breast cancer
Recommended dilution: 40-200
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml225592(JPT1 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml225592(JPT1 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 5000-10000
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Anti-JPT1 antibody
询价
