Product overview
Description Anti-PPP2R3A rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human PPP2R3A
Reactivity Human
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol PPP2R3A
Full name protein phosphatase 2, regulatory subunit B'', alpha
Synonyms PR72; PR130; PPP2R3
Swissprot Q06190
Target Background
This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human breast cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 50-200
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml262078(PPP2R3A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml262078(PPP2R3A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:130 kDa
Positive control:293T and PC3 cells
Recommended dilution: 200-1000