Anti-PPM1F antibody

Anti-PPM1F antibody

Cat. No.     JLC162075  
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PPM1F rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human PPM1F
Reactivity                 Human
Content                     0.8 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 PPM1F
Full name                 protein phosphatase, Mg2+/Mn2+ dependent, 1F
Synonyms    CAMKP; FEM-2; POPX2; hFEM-2; CaMKPase
Swissprot    P49593

Target Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase.