Anti-WNK3 antibody

Anti-WNK3 antibody

Cat. No.     JK262601 
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-WNK3 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human WNK3
Reactivity                 Human, Mouse
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 WNK3
Full name                 WNK lysine deficient protein kinase 3
Synonyms    PRKWNK3
Swissprot    Q9BYP7

Target Background
This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.