Product overview
Description Anti-WNK1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human WNK1
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol WNK1
Full name WNK lysine deficient protein kinase 1
Synonyms KDP; PSK; p65; HSN2; HSAN2; PRKWNK1; PPP1R167
Swissprot Q9H4A3
Target Background
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.