Anti-TRPM6 antibody

Anti-TRPM6 antibody

Cat. No.     JK262419
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-TRPM6 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human TRPM6
Reactivity                 Human
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 TRPM6
Full name                 transient receptor potential cation channel, subfamily M, member 6
Synonyms    HSH; HMGX; HOMG; CHAK2; HOMG1
Swissprot    Q9BX84

Target Background
This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.