Anti-TGM1 antibody

Anti-TGM1 antibody

Cat. No.    JK262404    
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-TGM1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human TGM1
Reactivity                 Human
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 TGM1
Full name                 transglutaminase 1
Synonyms    LI; KTG; LI1; TGK; ICR2; ARCI1; TGASE
Swissprot    P22735

Target Background
The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).