FITC标记的G蛋白偶联受体1抗体

FITC标记的G蛋白偶联受体1抗体

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  • ¥2980
  • LMAI Bio
  • LM-12019R-FITC
  • 中国/美国/欧洲
  • 2025年07月13日
  • ICC=1:50-200 IF=1:50-200
  • Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
  • Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-12019R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-GPR1/FITC

    • 抗体名

      Anti-GPR1/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      ICC=1:50-200 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的G蛋白偶联受体1抗体
    英文名称 Anti-GPR1/FITC
    中文名称 FITC标记的G蛋白偶联受体1抗体
    别    名 G protein coupled receptor 1; G-protein coupled receptor 1; GPR1; GPCR1/GPR1; GPR1_HUMAN.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 神经生物学  信号转导  细胞膜受体  G蛋白偶联受体  G蛋白信号  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
    产品应用 ICC=1:50-200 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 41kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GPR1
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. Gpr1 is required for yeast-to-hypha transition on various solid hypha-inducing media, and important for yeast cell morphology. It activates guanine nucleotide exchange on Gpa2 which stimulates cAMP synthesis by glucose. In Saccharomyces cerevisiae, Gpr1 is necessary for filamentous and invasive growth.

    Function:
    Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation. Can act as a coreceptor for HIV-1.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Expressed in hippocampus.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    Database links:
    Entrez Gene: 2825 Human
    Entrez Gene: 25457 Rat
    Omim: 600239 Human
    SwissProt: P46091 Human
    SwissProt: P46090 Rat
    Unigene: 184907 Human
    Unigene: 81208 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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