Product overview Description Anti-RUVBL2 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human RUVBL2 Reactivity Human, Mouse Content 0.54 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol RUVBL2 Full name RuvB like AAA ATPase 2 Synonyms RVB2; TIH2; ECP51; TIP48; CGI-46; ECP-51; INO80J; REPTIN; TIP49B; TAP54-beta Swissprot Q9Y230
Target Background This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
Applications Immunohistochemistry Predicted cell location: Nucleus and Cytoplasm Positive control: Human breast cancer Recommended dilution: 30-150
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml225066(RUVBL2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)