Product overview Description Anti-GCSAM rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human GCSAM
Reactivity Human
Content 1.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol GCSAM
Full name germinal center-associated, signaling and motility
Synonyms HGAL; GCAT2; GCET2
Swissprot Q8N6F7
Target Background This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms.