Anti-RHOBTB2 antibody

Anti-RHOBTB2 antibody

Cat. No.     JLC161608
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-RHOBTB2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human RHOBTB2
Reactivity                 Human, Mouse, Rat
Content                     0.8 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 RHOBTB2
Full name                 Rho-related BTB domain containing 2
Synonyms    DBC2
Swissprot    Q9BYZ6

Target Background
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.