Anti-MYCN antibody

Anti-MYCN antibody

Cat. No.     JK261964      
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-MYCN rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human MYCN
Reactivity                 Human, Mouse, Rat
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 MYCN
Full name                 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
Synonyms    NMYC; ODED; MODED; N-myc; bHLHe37
Swissprot    P04198

Target Background
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.