Anti-Ly6a antibody

Anti-Ly6a antibody

Cat. No.     JLC161191
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-Ly6a rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of mouse Ly6a
Reactivity                 Human, Mouse
Content                     0.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 Ly6a
Full name                 lymphocyte antigen 6 complex, locus A
Synonyms    TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1
Swissprot    P05533

Target Background
The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The Ly-6 alloantigens represent a family of phosphatidylinositol anchored proteins that play a role in the process of T lymphocyte activation. Ly-6 expression is commonly induced on T and B lymphocytes after activation by mitogens. Ly-6A/E is a phosphatidylinositol-linked transmembrane member of the Ly-6 family that is produced in humans after 4 weeks of age. ©-interferon and TNF regulate Ly-6A/E at the level of transcription and mRNA stabilization in certain thymocytes and T-cells.