Product overview Description Anti-U2AF2 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human U2AF2 Reactivity Human, Mouse Content 0.4 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol U2AF2 Full name U2 small nuclear RNA auxiliary factor 2 Synonyms U2AF65 Swissprot P26368
Target Background U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
Applications Immunohistochemistry Predicted cell location: Nucleus Positive control: Human esophagus cancer Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml224125(U2AF2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)