Product overview
Description Anti-BCLAF1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human BCLAF1
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol BCLAF1
Full name BCL2-associated transcription factor 1
Synonyms BTF; bK211L9.1
Swissprot Q9NYF8
Target Background
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.