Anti-NLRP7 antibody

Anti-NLRP7 antibody

Cat. No.     JK261456    
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-NLRP7 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human NLRP7
Reactivity                 Human
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 NLRP7
Full name                 NLR family, pyrin domain containing 7
Synonyms    HYDM; PAN7; NALP7; NOD12; PYPAF3; CLR19.4
Swissprot    Q8WX94

Target Background
This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.