人乳铁蛋白|Human lactoferrin|天然蛋白（人

Product types

Native Protein

Classification

Storage Protein

Research areas

Cardiovascular

Target / Protein

Human lactoferrin

Intended Use

ELISA,WB,SDS-PAGE

Protein length

Full length protein

Species of origin

Purified from human milk

Purity

>95%(SDS-PAGE)

Relevance

Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.

Storage Buffer

PBS, pH 7.4

Form

Liquid

Alias

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