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人AANAT重组蛋白Aralkylamine N-acety

ltransferaseHuman Serotonin N-acetyltransferase(AANAT)蛋白
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  • ¥1836
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  • CN
  • CSB-EP623090HU
  • 2026年01月20日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.

    • 保质期

      Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    • 英文名

      Recombinant Human Serotonin N-acetyltransferase (AANAT)

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 规格

      20μg


    英文名称:

    Recombinant Human Serotonin N-acetyltransferase (AANAT)

    品名简称:

    Recombinant Human AANAT protein

    货号:

    CSB-EP623090HU

    规格:

    20μg

    价格:

    1836

    LC-MS/Western Blot:

    /

    SDS-PAGE:

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    纯度:

    Greater than 85% as determined by SDS-PAGE.

    内毒素:

    Not test

    生物活性:

    /

    基因名:

    AANAT

    Uniprot No.:

    Q16613

    别名:

    Aralkylamine N-acetyltransferase

    种属:

    Homo sapiens (Human)

    蛋白长度:

    Full Length

    来源:

    E.coli

    分子量:

    51.8 kDa

    表达区域:

    1-207aa

    氨基酸序列:

    MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVLGVCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC

    蛋白标签:

    N-terminal 10xHis-GST-tagged

    产品提供形式:

    Liquid or Lyophilized powder

    缓冲液:

    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

    储存条件:

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

    保质期:

    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    货期:

    3-7 business days

    注意事项:

    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    功能1:

    Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.

    功能2:

    Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.

    文献:

    "cAMP regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation." Coon S.L., Weller J.L., Korf H.-W., Namboodiri M.A., Rollag M., Klein D.C. J. Biol. Chem. 276:24097-24107(2001)

    研究领域:

    Neuroscience

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    相关实验
    • Biochemical Characterization of a Testis-Predominant Isoform of N-Alpha Acetyltransferase

      N-alpha protein acetylation, catalyzed by N-alpha acetyltransferase complex, is a common protein �modification process in eukaryotic cells. Despite its widespread occurrence, the biological significance of this modification process

    • Characterization of 5‐HT1A,B and 5‐HT2A,C Serotonin Receptor Binding

      . 4‐(2'‐Methoxyphenyl)‐1‐[2'‐[N‐(2″‐pyridinyl)‐p‐iodobenzamido]ethyl] piperazine and 4‐(2'‐methoxyphenyl)‐1‐[2'‐[N‐(2″‐pyridinyl)‐p‐fluorobenzamido]ethyl]piperazine, two new antagonists at pre‐and postsynaptic serotonin‐1A receptors. J. Pharmacol. Exp. Ther. 277:661‐70

    • 近交后引起的变化

      后,动物的杂合性逐渐降低,因而纯度逐渐增高,使基因位点变为纯合子,使它们的表现型趋向一致性,如A与a基因频率相同,但基因型分配变化,经过一定代数的兄妹交配,则不再有杂合子,而获得遗传稳定的AAaa近交品系,见表3-1。同胞兄妹或亲子交配连续20代以上就培育成近交系,为了保持该系的遗传特点,必须继续近交,并不得因突变或遗传漂移而丢失。 表3-1  近交引起的基因纯合情况 P(A)=0.5 p(a)=0.5 代数 各 种 基 因 的 比 例 纯合子(野鼠色)AA

    图标技术资料

    暂无技术资料 索取技术资料

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    人AANAT重组蛋白Aralkylamine N-acetyltransferaseHuman Serotonin N-acetyltransferase(AANAT)蛋白
    ¥1836