Anti-LRP8 antibody

Anti-LRP8 antibody

Cat. No.     JK261297    
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-LRP8 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human LRP8
Reactivity                 Human, Mouse
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 LRP8
Full name                 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Synonyms    MCI1; LRP-8; APOER2; HSZ75190
Swissprot    Q14114

Target Background
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.