人PTN重组蛋白PTN, HBBM, Heparin-bin

英文名称：

Recombinant Human Pleiotrophin protein (PTN) (Active)

品名简称：

Recombinant Human PTN protein (Active)

货号：

CSB-AP002931HU

规格:

5μg

价格：

852

LC-MS/Western Blot：

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SDS-PAGE：

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纯度：

>96% as determined by SDS-PAGE.

内毒素：

Less than 1.0 EU/μg as determined by LAL method.

生物活性：

Fully biologically active when compared to standard. The biological activity was measured by its ability to enhance neurite outgrowth of E16­E18 rat embryonic cortical neurons, when neurons were plated on 96 well culture plates that had been pre­coated with 100 µl/well of a solution of 5­10 µg/ml rHuPTN.

基因名：

PTN

Uniprot No.：

P21246

别名：

PTN, HBBM, Heparin-binding growth factor 8, HBGF-8, Heparin-binding growth-associated molecule

种属：

Homo sapiens (Human)

蛋白长度：

Full Length of Mature Protein

来源：

E.Coli

分子量：

15.3 kDa

表达区域：

33-168aa

氨基酸序列：

GKKEKPEKKVKKSDCGEWQWSVCVPTSGDCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGSLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD

蛋白标签：

Tag-Free

产品提供形式：

Lyophilized powder

缓冲液：

Lyophilized from a 0.2 μm filtered PBS, pH 7.4

储存条件：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

货期：

5-10 business days

注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

功能1：

Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. {ECO:0000269|PubMed:11278720, ECO:0000269|PubMed:1768439}.

功能2：

Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells

文献：

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研究领域：

Immunology

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