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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Parathyroid hormone protein (PTH) (Active)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
100μg
英文名称:
Recombinant Human Parathyroid hormone protein (PTH) (Active)品名简称:
Recombinant Human PTH protein (Active)货号:
CSB-AP000051HU规格:
100μg价格:
3504LC-MS/Western Blot:
/SDS-PAGE:
/纯度:
>97% as determined by SDS-PAGE.内毒素:
Less than 1.0 EU/μg as determined by LAL method.生物活性:
Fully biologically active when compared to standard. The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg.基因名:
PTHUniprot No.:
P01270别名:
PTH, Parathyrin种属:
Homo sapiens (Human)蛋白长度:
Full Length of Mature Protein来源:
E.Coli分子量:
9.4 kDa表达区域:
32-115aa氨基酸序列:
SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKEDNVLVESHEKSLGEADKADVNVLTKAKSQ蛋白标签:
Tag-Free产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 µm filtered PBS, pH 7.4储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
5-10 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. {ECO:0000269|PubMed:21076856}.功能2:
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.文献:
/研究领域:
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文献和实验甲状旁腺激素(parathyroid hormone,PTH)
甲状旁腺主细胞分泌的肽类激素。正常人血浆PTH含量约1毫微克/毫升,最高可达6毫微克/毫升。其主要靶器官是骨、肾和小肠,调节钙、磷代谢,最终效应是升血钙,降低血磷:(1)对骨的作用。PTH刺激骨质吸收,动员骨的钙、磷入血。可分为快速效应和慢速效应两个时相。快速效应数分钟内即可发生,作用于骨细胞膜系统。骨细胞膜系统是由骨细胞和成骨细胞组成的一层膜,除破骨细胞邻近的区域外,覆盖全部骨表面和腔隙表面,从而在骨质与细胞外液之间形成可通透性屏障。这层膜与骨质之间有少量滑液,细胞外液侧
In Vivo Parathyroid Hormone Treatments and RNA Isolation and Analysis
Intermittent parathyroid hormone (PTH) administration increases bone formation and bone mass and is being used as a therapy for osteoporosis. By contrast, chronic hyperparathyroidism results in the metabolic bone disease osteitis fibrosa
简写为PTH。是由甲状旁腺分泌的激素。由 84个氨基酸构成的多肽。此激素宜接作用于骨组织,引起听谓的骨吸收,可使骨中钙向四中释放。因此,当此激素发挥作用时,血中钙浓度将上升。另外,它也能直接作用于肾脏,在加强磷、钠、钾排泄的同时可使 Ca 、 Mg 、 H 的排泄降低。调节甲状旁腺素分泌的是血钙浓度,此激素的分泌速率与血钙浓度成反比。
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