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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mouse Interleukin-4 protein (Il4) (Active)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
5μg
英文名称:
Recombinant Mouse Interleukin-4 protein (Il4) (Active)品名简称:
Recombinant Mouse Il4 protein (Active)货号:
CSB-AP003301MO规格:
5μg价格:
852LC-MS/Western Blot:
/SDS-PAGE:
/纯度:
>97% as determined by SDS-PAGE.内毒素:
Less than 1.0 EU/μg as determined by LAL method.生物活性:
Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant prolifiration of Murine HT-2 cells is less then 2 ng/ml, corresponding to a Specific Activity of > 5 × 105 IU/mg.基因名:
Il4Uniprot No.:
P07750别名:
IL-4, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1, IGG1 induction factor种属:
Mus musculus (Mouse)蛋白长度:
Full Length of Mature Protein来源:
E.Coli分子量:
13.5 kDa表达区域:
21-140aa氨基酸序列:
M+HIHGCDKNHLREIIGILNEVTGEGTPCTEMDVPNVLTATKNTTESELVCRASKVLRIFYLKHGKTPCLKKNSSVLMELQRLFRAFRCLDSSISCTMNESKSTSLKDFLESLKSIMQMDYS蛋白标签:
Tag-Free产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 µm filtered , PBS, pH 7.4储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
5-10 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.功能2:
Participates in at least several B-cell activation processes as well as of other cell types文献:
/研究领域:
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文献和实验Transplantation Models to Characterize the Mechanisms of Stem Cell–Induced Islet Regeneration
. Hakonen, E., Ustinov, J., Mathijs, I., Palgi, J., Bouwens, L., Miettinen, P.J., and Otonkoski, T. 2011. Epidermal growth factor (EGF)‐receptor signalling is needed for murine beta cell mass expansion
【翻译】Development trends for monoclonal antibody cancer therapeutics
, both of which could inhibit proliferation of targeted cells and prevent the advance of cancerous disease. Three approved unmodified mAbs (all IgG1) are believed to function primarily by blocking epidermal growth factor receptor (EGFR, also known as HER1) — cetuximab (Erbitux
刺激因子-1 (B cell stimulating factor-1, BSF-1)、T细胞生长因子-2 (T cell growth factor-2, TCGF-2)。1986年基因克隆成功,国际统一命名为白细胞介素4(interleukin 4, IL-4)。 IL-4对于B细胞、T细胞、肥大细胞、巨噬细胞和造细胞都有免疫 调节作用。 人类IL-4主要由活化T细胞产生。在小鼠由Th2亚群产生。人与鼠IL-4 DNA水平上有70%同源性, IL-4前体蛋白从N 端到91位氨基酸以及C 端
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