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人IL21重组蛋白IL-21,Human Interleuk

in-21 protein(IL21)(Active)蛋白
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  • ¥2124
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  • CN
  • CSB-AP001881HU
  • 2026年01月20日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.

    • 保质期

      Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    • 英文名

      Recombinant Human Interleukin-21 protein (IL21) (Active)

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 规格

      10μg


    英文名称:

    Recombinant Human Interleukin-21 protein (IL21) (Active)

    品名简称:

    Recombinant Human IL21 protein (Active)

    货号:

    CSB-AP001881HU

    规格:

    10μg

    价格:

    2124

    LC-MS/Western Blot:

    /

    SDS-PAGE:

    /

    纯度:

    >97% as determined by SDS-PAGE.

    内毒素:

    Less than 1.0 EU/μg as determined by LAL method.

    生物活性:

    Fully biologically active when compared to standard. The ED50 as determined by by a cell proliferation assay using human N1186 T cells is less than 20 ng/ml, corresponding to a specific activity of > 5.0 × 104 IU/mg.

    基因名:

    IL21

    Uniprot No.:

    Q9HBE4

    别名:

    IL-21,

    种属:

    Homo sapiens (Human)

    蛋白长度:

    Full Length of Mature Protein

    来源:

    E.Coli

    分子量:

    15.4 kDa

    表达区域:

    23-155aa

    氨基酸序列:

    QGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS

    蛋白标签:

    Tag-Free

    产品提供形式:

    Lyophilized powder

    缓冲液:

    Lyophilized from a 0.2 µm filtered PBS, pH 7.4

    储存条件:

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

    保质期:

    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    货期:

    5-10 business days

    注意事项:

    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    功能1:

    Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. {ECO:0000250, ECO:0000269|PubMed:11081504, ECO:0000269|PubMed:15178704}.

    功能2:

    Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

    文献:

    /

    研究领域:

    Immunology

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    相关实验
    • 白介素21IL21)在人生物样本中的精确检测实验

      DL-IL21-HuOverview:Other names:Za11Function:Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation

    • Persongen 新型 NK 细胞扩增技术

      基础。 传统的NK细胞扩增技术是在NK细胞培养体系中添加IL2、IL15等细胞因子以促进NK细胞增殖,但由于扩增效率不高且纯度不够未能得到广泛应用。近年来,有人采用基因工程的方法在K562细胞上同时表达IL-15、CD137L 等分子, 并以此细胞来刺激NK细胞的增殖。IL-15和CD137L联合刺激是PBMC 中NK细胞特异性扩增的基础:作为膜蛋白,通过细胞间的接触刺激,用以诱导NK细胞扩增。IL15能够促进NK细胞的分化成熟,而IL21能够联合IL15分子促进NK细胞的分化成熟,所以本研究在稳定

    • 白细胞介素interleukin

      ,以前曾以淋巴细胞活化因子( lymphocyte activating factor)。细胞促进蛋白质( mitogenic protein)以及 B细胞活化因子( B cell- activating factor)等七种名称称之。而 IL2属于淋巴细胞活素,以前曾以胸腺细胞刺激因子( thymocyte stimulating factor)、 T细胞生长因子( T cell growth factor)等六种名称称之。  

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