- 询价
- gelatins
- JLC223600
- 上海
- 2025年07月13日
- Rabbit
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- 详细信息
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-ZFAND5 antibody
- 宿主：
Rabbit
- 浓度：
1.4 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-ZFAND5 antibody
Cat. No. JLC223600
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-ZFAND5 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Full length fusion protein
Reactivity Human, Mouse, Rat
Content 1.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ZFAND5
Full name zinc finger, AN1-type domain 5
Synonyms ZA20D2; ZNF216; ZFAND5A
Swissprot O76080
Target Background
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm or Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm or Nucleus
Positive control: Human lung cancer
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ml223600(ZFAND5 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using ml223600(ZFAND5 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
Western blotting
Predicted band size:23 kDa
Positive control:Mouse fat tissue lysate
Recommended dilution: 500-2000
Gel: 8%SDS-PAGE
Lysate: 40 μg
Lane: Mouse fat tissue lysate
Primary antibody: ml223600(ZFAND5 Antibody) at dilution 1/500
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 1 minute
ELISA
Recommended dilution: 5000-10000
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Anti-ZFAND5 antibody
询价
