Product overview Description Anti-SLC12A6 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Synthetic peptide of human SLC12A6 Reactivity Human Content 0.3 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol SLC12A6 Full name Solute carrier family 12 (potassium/chloride transporters), member 6 Synonyms KCC3, ACCPN, KCC3A, KCC3B Swissprot Q9UHW9
Target Background This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.
Applications Immunohistochemistry Predicted cell location: Cytoplasm Positive control: Human breast cancer Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml260738(SLC12A6 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)