Product overview
Description Anti-DCLK1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human DCLK1
Reactivity Human, Mouse
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol DCLK1
Full name doublecortin-like kinase 1
Synonyms CL1; DCLK; CLICK1; DCDC3A; DCAMKL1
Swissprot O15075
Target Background
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity.