Product overview Description Anti-TAF12 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human TAF12 Reactivity Human, Mouse Content 0.4 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol TAF12 Full name TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa Synonyms TAF2J; TAFII20 Swissprot Q16514
Target Background Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins.
Applications Immunohistochemistry Predicted cell location: Cytoplasm and Nucleus Positive control: Human liver cancer Recommended dilution: 25-100 Predicted cell location: Cytoplasm and Nucleus Positive control: Human esophagus cancer Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml223279(TAF12 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml223279(TAF12 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)