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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Intersectin-1 protein (773-916AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
HRP
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q15811
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA
- 浓度:
>95%,Protein G purified
- 靶点:
ITSN1
- 抗体英文名:
ITSN1 Antibody, HRP conjugated
- 抗体名:
Src homology 3 domain containing protein antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Acts as guanine nucleotide exchange factor (GEF) specific for the CDC42 GTPase (By similarity). Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Isoform 1 could be involved in brain-specific synaptic vesicle recycling. Inhibits ARHGAP31 activity toward RAC1.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验BIAcore Analysis to Test Phosphopeptide-SH2 Domain Interactions
messages, has been an enormous breakthrough (1 ). Among these transducing domains, the src homology 2 (SH2) domains are specialized in the interaction with the phosphorylated forms of tyrosine residues (2 ). SH2 domains are classically 100 amino acids
ARF GTPase-Activating Protein 1
guanine-nucleotideexchange proteins containing a Sec7-homology domain (for review see ref . 1 ). The subsequent deactivation of ARFs and their dissociation from membranes depends on the hydrolysis of bound GTP. However, ARF proteins are devoid
protein SRC homology 2(SH2) protein of Beta-cells (SHB) for the development of both pancreatic β-cells and blood vessels. SHB is an SH2 domain-containing adapter protein involved in the generation of signaling complexes in response to activation
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