文献支持
CENPA抗体CENPA兔多抗抗体Histone H3-li
ke centromeric protein A antibody抗体CENPA (Ab-7) Antibody抗体- ￥660 - 2420
- CUSABIO
- CN
- CSB-PA005205OA07nphHU
- 2025年07月14日
- ELISA, IHC; Recommended dilution: IHC:1:10-1:100
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Peptide sequence around site of Ser (7) derived from Human Histone H3-like centromeric protein A
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
P49450
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, IHC; Recommended dilution: IHC:1:10-1:100
- 浓度：
>95%,Antigen Affinity Purified
- 靶点：
CENPA
- 抗体英文名：
CENPA (Ab-7) Antibody
- 抗体名：
Histone H3-like centromeric protein A antibody
- 规格：
100μl/50μl/20μl
| 规格： | 100μl | 产品价格： | ￥2420.0 |
|---|---|---|---|
| 规格： | 50μl | 产品价格： | ￥1320.0 |
| 规格： | 20μl | 产品价格： | ￥660.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes (PubMed:7962047, PubMed:9024683, PubMed:11756469, PubMed:14667408, PubMed:15702419, PubMed:15475964, PubMed:15282608, PubMed:17651496, PubMed:19114591, PubMed:27499292, PubMed:20739937). Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore (PubMed:18072184). The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3 (PubMed:27499292, PubMed:26878239). May serve as an epigenetic mark that propagates centromere identity through replication and cell division (PubMed:15475964, PubMed:15282608, PubMed:26878239, PubMed:20739937, PubMed:21478274). Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis (PubMed:11756469, PubMed:14667408, PubMed:18072184, PubMed:23818633, PubMed:25556658, PubMed:27499292).风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
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文献支持
CENPA抗体CENPA兔多抗抗体Histone H3-like centromeric protein A antibody抗体CENPA (Ab-7) Antibody抗体
￥660 - 2420
