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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human G-protein coupled receptor family C group 6 member A protein (403-581AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Biotin
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q5T6X5
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA
- 浓度:
>95%,Protein G purified
- 靶点:
GPRC6A
- 抗体英文名:
GPRC6A Antibody, Biotin conjugated
- 抗体名:
seven transmembrane helix receptor antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalcin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Transmembrane Signaling by Receptor Oligomerization
(4 ). Intramolecular mechanisms that have been proposed involve ligand-induced conformational changes that are propagated through the single transmembrane α-helix or alter the association of the receptor with the membrane (a “push-pull” model). Objections
Role of Receptor Tyrosine Kinases in Lung Cancer
, in both lung and other tissues, have been identified (1 ). The receptors contain an N-terminal extracellular ligand-binding domain, a single transmembrane α helix, and a cytosolic C-terminal domain with tyrosine kinase activity. The binding of growth factors
作为免疫反应调节的细胞而发挥作用,但这些细胞的Fc受体的作用尚不甚明了。在人体,具有对IgM的Fc受体的细胞,是B细胞的助细胞,以及具有对IgG的受体细胞,是作为抑制细胞而起作用。(4)对肥大细胞的Fc受体结合的IgE,其进一步与抗原结合时,肥大细胞可释放出引起“即发型”过敏症因子。(5)非淋巴细胞性的某种细胞(K细胞),可与癌细胞同异种细胞结合的IgG的Fc部分结合,给这些细胞以障碍,这种现象称为抗体依赖性细胞障碍作用(antibody dependent cellular cytotoxi
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