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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Sortilin-related receptor protein (525-744AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q92673
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- 浓度:
>95%,Protein G purified
- 靶点:
SORL1
- 抗体英文名:
SORL1 Antibody
- 抗体名:
Sorting protein-related receptor containing LDLR class A repeats antibody
- 规格:
100μg/50μg/20μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
| 规格: | 20μg | 产品价格: | ¥440.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. Involved in APP trafficking to and from the Golgi apparatus. It probably acts as a sorting receptor that protects APP from trafficking to late endosome and from processing into amyloid beta, thereby reducing the burden of amyloidogenic peptide formation. Involved in the regulation of smooth muscle cells migration, probably through PLAUR binding and decreased internalization.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验) ( 2 - 4 ). The proximal promoter, containing the hormone response elements (HREs), and binding sites for nuclear factor 1 (NF1), TATA binding protein (TBP), and octamer transcription factors (OTFs) is encompassed by nucleosomes A and B ( 2 , 5 ). Analysis
RNA AND PROTEIN EXTRACTION FROM THE SAME SAMPLE
and pour into a 15 mL centrifuge tube. Depending on the kind of tissue, extra extraction buffer and b -mercaptoethanol may be required NOTE: for protein analysis: remove ~0.5-1.0 mL into eppendorf tube containing 1-5 m L of 0.1M PMSF. Mix
Protein Microarrays for Identification of Novel Extracellular Protein‐Protein Interactions
. Instead, the use of protein microarrays appears to be a robust and efficient method for the identification of interactions among the members of this class of protein. This unit describes methods for extracellular protein microarray production, screening
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