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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-GADD45B antibody
- 宿主:
Rabbit
- 浓度:
0.6 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JLC222399
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-GADD45B rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human GADD45B
Reactivity Human, Mouse
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol GADD45B
Full name growth arrest and DNA-damage-inducible, beta
Synonyms MYD118; GADD45BETA
Swissprot O75293
Target Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 50-200
The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ml222399(GADD45B Antibody) at dilution 1/40. (Original magnification: ×200) The image is immunohistochemistry of paraffin-embedded Human brain tissue using ml222399(GADD45B Antibody) at dilution 1/40. (Original magnification: ×200)
ELISA
Recommended dilution: 2000-5000
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