Product overview Description Anti-ARIH2 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human ARIH2 Reactivity Human, Mouse Content 1.38 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol ARIH2 Full name ariadne RBR E3 ubiquitin protein ligase 2 Synonyms ARI2; TRIAD1 Swissprot O95376
Target Background The protein encoded by this gene is an E3 ubiquitin-protein ligase that polyubiquitinates some proteins, tagging them for degradation. The encoded protein upregulates p53 in some cancer cells and may inhibit myelopoiesis. Several transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been determined yet.